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Filtered Search Results
Medchemexpress LLC Boc-NH-PEG10-NHS ester | 3075546-11-8 | 98.0% | C32H58N2O16 | 100 MG
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Boc-NH-PEG10-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules with two ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Utilizes the intracellular ubiquitin-proteasome system
- For research use only
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Apexbio Technology LLC His-tag Protein Purification Kit (Non-Denaturant) 10ml
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The His-tag Protein Purification Kit (Non-Denaturant) is designed for the affinity purification of recombinant proteins containing polyhistidine (His) tags under native non-denaturing conditions The kit utilizes metal ion affinity chromatography where the His-tag binds selectively to immobilized divalent metal ions on the resin matrix enabling targeted isolation without disrupting protein conformation or activity This approach preserves the protein s native structure supporting downstream functional analyses such as enzymatic assays protein-protein interaction studies and structural characterization The kit is widely applicable in molecular biology and protein biochemistry research
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Medchemexpress LLC Hippuryl-His-Leu-OH hydrate (N-Benzoyl-Gly-His-Leu hydrate) | 207386-83-2 | 99.7% | 429.47 | 50 MG
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Hippuryl-His-Leu-OH hydrate (N-Benzoyl-Gly-His-Leu hydrate) is a specific substrate for angiotensin-converting enzyme (ACE) I, used as a molecular tool for detecting ACE activity in in vitro experiments. It is hydrolyzed by ACE through competitive binding, producing hippuric acid, which can be quantified to assess ACE activity or screen for ACE inhibitors. The released His-Leu can also be detected via fluorescence.
- Specific substrate for angiotensin-converting enzyme (ACE) I.
- Molecular tool for detecting ACE activity in vitro.
- Hydrolyzed by ACE to produce hippuric acid.
- Quantitatively assesses ACE activity.
- Screens for ACE inhibitors.
- Released His-Leu detectable via fluorescence.
- Applicable for hypertension and cardiovascular disease research.
- Used in studying changes in ACE activity during physiological and pathological processes.
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Chem-Impex International, Inc. Boc-His(1-Me)-OH | 61070-20-0 | MFCD00076944 | 1G
Boc-His(1-Me)-OH, 61070-20-0, MFCD00076944, 1G
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Medchemexpress LLC DL-Histidine | 4998-57-6 | 99.77% | 155.16 | 100 G
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DL-Histidine is a histidine derivative. Amino acids and amino acid derivatives are commercially utilized as ergogenic supplements, recognized for their benefits as ergogenic dietary substances.
- Impacts the secretion of anabolic hormones
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Helps prevent exercise-induced muscle damage
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STA PHARMACEUTICAL US LLC Fmoc-L-His(Fmoc)-OH | 25 g | CAS 98929-98-7 | MDL MFCD00070658
Fmoc-L-His(Fmoc)-OH is a Amino Acid reagent (Subcategory: His) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 98929-98-7
- MDL: MFCD00070658
- InChIKey: WTBXFPFCUZKREB-XIFFEERXSA-N
- Molecular Weight: 599.643
- Molecular Formula: C36H29N3O6
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29332990
- Country Of Origin: China
- IUPAC: Na,Nt-bis(((9H-fluoren-9-yl)methoxy)carbonyl)-L-histidine
- SMILES: O=C(N1C=NC(C[C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C(O)=O)=C1)OCC5C6=CC=CC=C6C7=CC=CC=C75
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CEM Corporation RESIN, FMOC-HIS(TRT)-WANG-P 5G
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Resin, Fmoc-His(Trt)-Wang-Protide, 5g
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Medchemexpress LLC Boc-His-OMe | 2488-14-4 | ≥97.0% | 269.30 | 10 G
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Boc-His-OMe is a histidine derivative commercially utilized as an ergogenic supplement. It is known to influence the secretion of anabolic hormones, provide fuel during exercise, improve mental performance under stressful conditions, and help prevent exercise-induced muscle damage. These compounds are recognized for their beneficial properties as ergogenic dietary substances.
- Histidine derivative
- Influences anabolic hormone secretion
- Provides fuel during exercise
- Improves mental performance under stressful conditions
- Helps prevent exercise-induced muscle damage
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Medchemexpress LLC L-Moses (dihydrochloride) | 2922480-38-2 | MFCD31563590 | 99.4% | 433.38 g/mol | C21H26Cl2N6 | 5 MG
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L-Moses (L-45) dihydrochloride is a cell-active chemical probe that selectively inhibits the p300/CBP-associated factor (PCAF) bromodomain, with a reported dissociation constant (Kd) of 126 nM. Supplied as the dihydrochloride salt, the compound is used in biochemical and cellular epigenetic assays to interrogate PCAF function and mechanism of bromodomain-mediated recognition.
- Potent, selective PCAF bromodomain inhibition (Kd 126 nM).
- Cell-active probe suitable for cellular assays.
- Supplied as dihydrochloride salt for stability and handling.
- High purity suitable for research (≈99.4% by LCMS).
- Molecular formula C21H26Cl2N6; molecular weight 433.38 g/mol.
- Available in small research pack sizes appropriate for screening and follow-up studies.
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Cayman Chemical Na-Boc-D-HIstIdIn 1g
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An amino acid building block; has been used in the synthesis of antimicrobial peptides, thyrotropin-releasing hormone enantiomers, and proteolysis-resistant peptide renin inhibitors
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Medchemexpress LLC TrigalNAc CBz | 186613-57-0 | 98.73% | 633.64 | 50 MG
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TriGalNAc CBz is a GalNAc derivative and an asialoglycoprotein receptor (ASGPR) ligand. It can be utilized for mRNA drug delivery and lysosomal targeted chimerism (LYTAC) studies. It functions as a linker for the synthesis of GalNAc-LYTACs, specifically binding to the ASGPR receptor in hepatocytes to transport the target protein and receptor complex to the endosome for degradation.
- GalNAc derivative
- ASGPR ligand
- Can be used for mRNA drug delivery
- Can be used for lysosomal targeted chimerism (LYTAC) studies
- Acts as a linker for the synthesis of GalNAc-LYTACs
- Binds specifically to the ASGPR receptor in hepatocytes
- Transports target protein and receptor complex to the endosome
- Enables target protein transport to the lysosome for degradation
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STA PHARMACEUTICAL US LLC Fmoc-D-His(Boc)-OH | 25 g | CAS 159631-28-4 | MDL MFCD00151927
Fmoc-D-His(Boc)-OH is a Amino Acid reagent (Subcategory: His) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 159631-28-4
- MDL: MFCD00151927
- InChIKey: ZRHPMMZWDWMKPD-JOCHJYFZSA-N
- Molecular Weight: 477.517
- Molecular Formula: C26H27N3O6
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29332990
- Country Of Origin: China
- IUPAC: Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-Nt-(tert-butoxycarbonyl)-D-histidine
- SMILES: CC(OC(N1C=C(C[C@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)N=C1)=O)(C)C
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eMolecules 645-35-2 | L-Histidine hydrochloride | MFCD00064556 | 5g
Combi-Blocks | L-Histidine hydrochloride | 5g | 537622000 | QM-5129 | 98.000 | 645-35-2 | MFCD00064556 | 191.620 | C6H10ClN3O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
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Chem-Impex International, Inc. Na-Fmoc-Nim-Boc-L-histidine | 81379-52-4 | MFCD00151928 | 1G
Na-Fmoc-Nim-Boc-L-histidine, 81379-52-4, MFCD00151928, 1G
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Medchemexpress LLC TriGalNAc CBz | 186613-57-0 | 98.7% | 633.64 | 25 MG
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TriGalNAc CBz is a GalNAc derivative and a tri-GalNAc asialoglycoprotein receptor (ASGPR) ligand. It can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies. It acts as a linker for the synthesis of GalNAc-LYTACs, binding to the ASGPR receptor in hepatocytes to transport the target protein and receptor complex to the endosome, where tri-GalNAc is released in the acidic environment for target protein degradation.
- GalNAc derivative
- ASGPR ligand
- Used for mRNA drug delivery
- Used for lysosomal targeted chimerism (LYTAC) studies
- Acts as a linker for synthesis of GalNAc-LYTACs
- Binds specifically to the ASGPR receptor expressed in hepatocytes
- Transports target protein and receptor complex to the endosome
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